Whilst not open source, I appreciate that the notes are locally stored in straightforward markdown. I no longer use Obsidian, but I appreciated how there was next to no platform lock-in (the only snag I experienced in moving to a different note taking approach was a couple of plugins that gave additional features. But that’s easy to avoid if portability of data is important)

“Constellation prize” is a funny title for this comic. I love it.

Doesn’t it only work if you then return to a lower altitude? I wonder how long the benefits last for.

Now that I think about it, I don’t actually know how this even works. Well I know what I’m going to go read about next.

Edit: My findings:

• At high altitude, cardiac output (the overall rate of blood pumped by the heart) increases, largely due to increased heart rate. This increased heart rate reduces as one acclimatises to high altitude (though I’m unsure of if it returns to baseline. It appears to be complex, and at least somewhat differing person by person. These individual differences may explain why some people experience health problems at high altitude, beyond the initial ill feelings caused from first arriving somewhere that’s high altitude)

• The stroke volume (volume of blood pumped by each beat of the heart) is lower at high altitudes. This does improve as one acclimatises, but not entirely. This seems to be affected by blood pressure stuff, such as reduced plasma volume at high altitude. It seems to be complex enough that we don’t fully understand how the various regulatory stuff works.

• Most of the acclimatisation occurs by increasing the number of red blood cells in the blood. The hormone erythropoietin, which usually exists at a low level in non-hypoxic conditions, stimulates the production of new red blood cells. At high altitude, the level of erythropoietin in the blood rises to around 1000 times its baseline level. Increased production of red blood cells happens for a few weeks, by which point, there is enough to make up for lower oxygen levels at high altitude.

• When returning to low altitude, it appears that the changes back to the baseline happen over a similar timeline.

Tangential fun fact: a red blood cell has a lifetime of around 4 months. A single red blood cell travels around 400 miles before it is old enough to be recycled by the body.

100% of people exposed to oxygen die.

Huh, interesting. To me, “moggy” is just a slang term for a cat, e.g. “who’s a pretty moggy?”. But also, I’ve only once met a cat that was of a particular breed, so perhaps the general nature of “moggy” for me stems from that. (For context, I am from the UK)

I’m not typically someone who squees over photos of other people’s pets, but those are two beautiful cats

The vets that I have experienced tend to use the human’s surname as the pet’s surname. If that’s the case with you also, it is humorous to imagine a cat’s chart basically saying “Cat [your last name]”

No no, you’ve got it the wrong way round: autism causes telescopes

Only a couple. I can imagine that “the user is not the enemy” may be a difficult sentiment for some people with heavily user-facing roles. I’m curious what federated service you’re interfacing with this from. I imagine that’s why you didn’t see the votes on your comment. I am posting this via Lemmy

Despite the downvotes you’ve received, I appreciate you posting this, because I am always jazzed to discover “classic” pieces that are new to me.

Seeing your reply in my inbox reminded me that I got up to get some ice-cream, but forgot again en route to the freezer. On the bright side, it means I still have ice-cream in my freezer

“Multiple new scylla songs too, Supergiant are spoiling us.”

Awesome. I love how catchy the Scylla songs are

Thanks for reminding me that I have ice cream in

Thank you for the reminder that I’ve been meaning to buy a menstrual cup.

I like that having a controller gives me more versatility in my seating position when gaming. At my desk, I can use either the controller or mouse and keyboard. If I get tired in that position, the long wire on my controller means I can sit elsewhere and play (my desk is positioned such that I can just rotate my monitor and play it from my sofa if I want).

I also enjoy that a controller is more portable than my mouse and keyboard for playing games on my laptop when away from home.

I am in this image and I don’t like it.

Look at the cute lil guy. He’s so pleased with his hat

I find the wide variety of ace experiences super interesting. For my part, I’m bi and also demisexual (and I have been working hard at practicing not ace-erasing myself).

An example of the interesting variety I mean is how libido and attraction aren’t necessarily coupled, and also that even besides those factors, there’s a spectrum of ace attitudes towards sex. I had a friend who had a high libido, but was also quite sex-repulsed. That is to say that she masturbated plenty, but had no inclination towards sex. This caused some tension when she entered into a romantic relationship with an allosexual woman who had some difficulty understanding an ace person being both sex repulsed and high libido (though tbf, my friend was learning how to navigate the line between enjoyable cuddles and unpleasantly sexual stuff. She also tried to fit into the model of aceness similar to what you describe, but she found that her discomfort with sex was such that it made her feel less close to her partner (in contrast to how our sex-ambivalent ace friends had described their experiences).

It’s hidden enough that I have had to provide tech support to my friends a few times on this. I think it’s easy to forget how expertise shapes our perspective on these things

“The only exception is like Stardew Valley, where they put the save directory in a normal folder.”

It’s been years since I played Stardew Valley, but stuff like this is why I consider myself a fan.