My personal experience has been that it’s games from the post-DOS era, especially PC games from the very late 90s and early 00s, that can be really tricky.
I’ve had better luck running games from that era from my GOG library via Lutris on Linux than Windows 10/11.
The ones that run in DOS Box are comparatively easy!
I use Aurora (the KDE version) as a software dev/ gaming machine. It’s great!