Definitely not, enshitification is real. I’ve gone from someone excited about new products to I don’t trust anything that I didn’t build. We are currently discussing moving our group chat off discord, but I’m biochemist and my circle are similar professions and I’m still learning how to properly host things.

In the before times we used hamachi, but it was hard. Eventually, Skype was born and it was good and easy. It worked like a phone and many StarCraft 2 team games were won. But Skype was corrupted by the many Nigerian princes and hot Ladies who only needed a few dollars to turn your life around. This corruption was then baked so deeply into windows it took registry edits to exorcise it. But all was good was we now had discord which took the ideas of hamachi and Skype and delived a better experience than both.

You’d be surprised how much money gets wasted of stupid projects and acquisitions in biotech because some suit think they understand science better than their R&D team. For analogy sake think about all the stupid shit Microsoft bought and killed or all the chat apps Google created and killed, this going to be Regeneron’s Skype.

If you really want to get your parents sequenced for your own personal use without it going into a database it’ll cost you about $500 per sample (cheaper if you know someone who can extract the DNA for you). You’ll get a set of fastq files for the reads that will cover almost their entire genome that you can then use with public databases or just store for future use. Another option is to sign up for a university study but you’ll have to be comfortable with their data use.

I honestly don’t know what they will do with snp data. These investors and VCs have been running scare peace articles for the last two years to drive the company into bankruptcy so that it could be sold and the data harvested. But I honestly think people are really overestimating the value of a dataset showing how different people are from a standard template. It’s good for ancestry and correlations but people forget they didn’t fully sequence samples. I fully expect the news cycle to change once they figure this out as they try to get people to resubmit DNA for nextgen sequencing, so they can try to salvage their investment.

My Rx580 has basically been on continuously since I bought it in like 2017/18. I used it to mine when I wasn’t gaming until it became unprofitable, then to process sequencing data for my dissertation project while not gaming, and now it’s in my server.

This was almost my gaming PC specs in 2020. Rx580 and 16gb more ram. It’s now my server running jellyfin and immich for my family.

I’m an American biochemist, I also never learned the english system because my school transitioned to metric too fast. The mental burden of trying to cook using english units after working all day in the lab using that same part of my brain leads me to just not want to cook 95% of the time. But when I do cook I have optimized processes for my few simple recipes. When I bake I usually use a metric recipe or convert a English one, and optimize it before making a large batch of something.

Slowly being turned towards the sea

I’m 11hrs in so far, and I’m hooked. The world building, gameplay and characters are amazing. I also really loved the music, especially inside the manor.

Aldi rice cooker. $18 and the most used tool in the kitchen

It tastes like ass, but over time you grow to enjoy the taste of ass, and eventually you prefer the taste of ass .

I eat tacos bell

If you live near a college campus, check out their recycling center or campus surplus. Lots of IT departments just toss UPS when they upgrade equipment regardless of battery status. I like to grab APC ones because the battery replacements are easy to find and there’s usually a YouTube video for the exact model with someone refurbing it.

Rtx 3070

Upgraded my highschool family desktop I took to college with a GeForce 8800 GT , used until I build a new pc with a Radeon 7970 GHz edition, which was replaced with a rx580 after the card passed away from light coin poisoning. Desktop is now running unRAID and my new main rig has a gtx 3070 in.

Halo

If you live near a college, check their surplus or recycling. I got a brother printer for the low price of fixing a paper jam.

I understand, and I definitely don’t fault anyone who likes the show or stuck through it. I just feel like too many shows I’ve been watching lately hasn’t been worth the slog to get through, and it’s been killing my excitement for franchises.

For example I haven’t watched house of the dragon because game of thrones rushed ending, Picard season 3 because of season 2, and I fell off the marvel train after Wanda vision, falcon and winter soldier, and she hulks endings, all shows that either ending in nothing burgers or wtf I guess we need to end somehow.

I don’t think anyone who sat down and watched through the first 3 episodes can honestly say the show is being review bombed. Im enjoyed Ashoka and Boba Fett and I honestly have no interest in wasting my time finishing the show.

It’s like the nothing burgers of the Disney star wars comics. The Darth Vader series was great, and I love the idea of bleeding light sabers red. But everyone other series leading into the last Jedi was a waste of time, and I bought and read every single one.